Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    844648-19-7

    Catalog No. EBD3332408

    CAS 844648-19-7

    Name 3-(3,5-difluorophenoxy)- Propanoic acid

    Get Quote
    Basic Information

    Synonyms: 3-(3,5-二氟苯氧基)丙酸 3-(3,5-二氟苯氧基)丙酸

    Molecular Formula: C9H8F2O3

    Molecular Weight: 202.15

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    3-(3,5-Difluorophenoxy)propanoic acid is a white to off-white crystalline powder with a molecular formula of C9H8F2O3. It is a carboxylic acid derivative featuring a phenoxypropanoic acid scaffold substituted with two fluorine atoms at the 3 and 5 positions of the phenyl ring. This compound serves as a key pharmaceutical intermediate. It is notably utilized in the synthesis of novel, potent, and selective peroxisome proliferator-activated receptor (PPAR) agonists. These agonists are investigated for their potential therapeutic applications in treating metabolic disorders such as type 2 diabetes and dyslipidemia. The 3,5-difluorophenoxy moiety is a critical structural element contributing to the biological activity and receptor binding affinity of the final drug candidates. As a bifunctional building block containing both a carboxylic acid and an aromatic ether linkage, it is also employed in organic synthesis for constructing more complex molecules. Standard safety precautions for handling laboratory chemicals should be observed.
    Physical Properties

    Storage: −20°C

    mg g kg ml l t