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    98519-65-4

    Catalog No. EBD76157

    CAS 98519-65-4

    Name 4-bromo-7-chloroquinoline

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    Basic Information

    Synonyms: 4-bromo-7-chloro-quinoline 4-brom-7-chlorchinolin 4-bromo-7-chloroquinoline quinoline,4-bromo-7-chloro- T66BNJEEIG 4-bromo-7-chloro-1-azanaphthalene

    Molecular Formula: C9H5BrClN

    Molecular Weight: 242.5

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    4-Bromo-7-chloroquinoline is a halogenated quinoline derivative. It serves as a versatile and crucial synthetic building block in medicinal chemistry. The presence of both bromine and chlorine atoms at the 4- and 7-positions, respectively, makes it a valuable substrate for various cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions. Its primary application is as a key intermediate in the synthesis of biologically active compounds, particularly pharmaceutical candidates. It is notably used in the development of kinase inhibitors and other therapeutic agents targeting various diseases. The quinoline core is a privileged scaffold in drug discovery, and the specific halogen substitution pattern allows for selective functionalization to create diverse molecular libraries. As a bifunctionalized heterocyclic compound, it is a common starting material in research and development laboratories. Its utility extends beyond specific drug programs, making it a standard reagent for constructing complex quinoline-based structures in both academic and industrial settings.
    Physical Properties
    Safety Information

    Packing Level: III

    Hazard Category: 6.1

    Transport Codes: 2811

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