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    98273-19-9

    Catalog No. EBD1110813

    CAS 98273-19-9

    Name Methyl 4,6-dichloropicolinate

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    Basic Information

    Synonyms: Methyl4,6-dichloropicolinate

    Molecular Formula: C7H5Cl2NO2

    Molecular Weight: 206.03

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    Methyl 4,6-dichloropicolinate is a white to off-white crystalline powder with a molecular formula of C7H5Cl2NO2. It is a halogenated pyridine derivative, specifically a methyl ester of a dichlorinated picolinic acid. This compound is a versatile and important chemical intermediate in organic synthesis. Its primary and most significant application is in the pharmaceutical industry as a key building block for the synthesis of various active pharmaceutical ingredients (APIs). It serves as a crucial precursor in the manufacturing of complex drug molecules, particularly those containing the pyridine scaffold. The presence of two chlorine atoms and an ester group makes it a reactive site for further functionalization, such as nucleophilic aromatic substitution and cross-coupling reactions, enabling the construction of diverse heterocyclic systems found in medicinal compounds. While its main use is as a pharmaceutical intermediate, its well-defined reactive sites also make it a valuable organic synthesis building block in research settings for constructing more complex molecules. Standard safety precautions for handling halogenated aromatic compounds should be observed.
    Physical Properties

    Melting Point: 78 - 82 °C

    Storage: 2-8°C

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