2-Amino-5-bromo-4-methylpyridine, CAS No. 98198-48-2

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98198-48-2

Catalog No. EBD22411

CAS 98198-48-2

Name 2-Amino-5-bromo-4-methylpyridine

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Basic Information

Synonyms: 5-bromo-4-methyl-pyridin-2-ylamine 5-bromo-4-methyl-2-pyridinylamine 2-amino-5-bromo-gamma-picoline 2-amino-5-bromo-4-picoline 2-amino-4-methyl-5-bromopyridine 2-amino-5-bromo-4-methylpyridine98% 2-amino-5-bromo-4-picoline(2-amino-5-bromo-4-methylpyridine) 2-Amino-5-Bromo-4-Methylpyridine 5-Bromo-4-Methylpyridin-2-Amine 2-amino-5-bromo-4-methylpyridinium 2-Amino-5-Bromo-4-methylpridine

Molecular Formula: C6H7BrN2

Molecular Weight: 187.04

MDL Number: MFCD03427660

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Amino-5-bromo-4-methylpyridine is a halogenated aminopyridine derivative. It features a pyridine ring substituted with an amino group at the 2-position, a bromine atom at the 5-position, and a methyl group at the 4-position. This structure makes it a versatile heterocyclic building block. This compound is primarily used as a key pharmaceutical intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its specific substitution pattern allows for further functionalization, particularly through cross-coupling reactions involving the bromine atom. It serves as a crucial precursor in the development of kinase inhibitors and other biologically active molecules targeting diverse therapeutic areas. As a bifunctional synthon containing both a reactive bromine and an amino group, it is also employed in organic synthesis and materials science research. It is commercially available from major chemical suppliers for research and development purposes.

Physical Properties

Melting Point: 148-151 °C(lit.)

Boiling Point: 254.2 °C at 760 mmHg

Flash Point: 107.5 °C

Density: 1.593 g/cm3

Analytical Data

Appearance: Light yellow crystal