2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose, CAS No. 97614-43-2

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

97614-43-2

Catalog No. EBD27

CAS 97614-43-2

Name 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose

Get Quote

Basic Information

Synonyms: 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-alpha-D-arabinofuranose 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-arabinofuranose 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose 1,3,5-tri-o-benzoyl-2-deoxy-2-fluoro-a-d-arabinofuranose 2-deoxy-2-fluoro-1,3,5-tri-o-benzoyl-a-d-arabinofuranose 2-fluoro-2deoxy-1,3,5-o-benzoyl-a-d-arabinofuranose 2-fluoro-2-deoxy-1,3,5-tribenzoyl-alpha-d-arabinofuranose 2-fluoro-2-deoxy-1,3,5-tri-o-benzoyl-alpha-d-arabinofuranose 2-fluoro-2-deoxy-1,3,5-tri-O-benzoyl-A-D-arabino 2-deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose FLuorosugar α-D-Arabinofuranose,2-deoxy-2-fluoro-,tribenzoate 2-deoxy-2-fluoro-1,3,5-tris-O-(phenylcarbonyl)-α-D-arabinofuranose 2-Fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-D-arabinofuranose 2-fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-D-arabino α-D-Arabinofuranose,2-deoxy-2-fluoro-,1,3,5-tribenzoate 2-Deoxy-2-fluoro-1,3,5-tribenzoate-alpha-D-arabinofuranose 2-Deoxy-2-fluoro-1,3,5-tri-O

Molecular Formula: C26H21FO7

Molecular Weight: 464.44

MDL Number: MFCD00083339

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides

Product Description:

2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose is a key fluorinated sugar building block. It features a fluorine atom at the C-2 position and benzoyl protecting groups on the 1, 3, and 5 hydroxyl groups, with an α-configuration at the anomeric center. This specific structure makes it a crucial precursor in nucleoside chemistry. Its primary application is in the synthesis of fluorinated nucleoside analogues, which are important active pharmaceutical ingredients (APIs) and prodrugs. Notably, it serves as a vital intermediate in the synthesis of sofosbuvir (a direct-acting antiviral drug for hepatitis C) and other investigational antiviral and anticancer nucleosides. The fluorine substitution and protected sugar moiety are essential for modulating the biological activity, metabolic stability, and pharmacokinetic properties of the final drug molecules. This compound is a specialized synthetic intermediate rather than a general-purpose reagent. It is handled under controlled conditions in research and industrial settings dedicated to nucleoside and antiviral drug development.

Physical Properties

Boiling Point: 584.1 °C at 760 mmHg

Flash Point: 295.7 °C

Density: 1.35 g/cm3

Storage: 2-8°C