2-Hydroxy-5-nitrobenzaldehyde, CAS No. 97-51-8

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97-51-8

Catalog No. EBD9819

CAS 97-51-8

Name 2-Hydroxy-5-nitrobenzaldehyde

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Basic Information

Synonyms: 2-Hydroxy-5-nitrobenzaldehyde 2-hydroxy5-nitrobenzaldehyae(5-nitrosalicylaldehyde) 2-hydroxy-5-nitro-benzaldehyd 5-nitro-salicylaldehyd -nitro-2-hydroxybenzaldehyde salicylaldehyde,5-nitro- timtec-bbsbb003885 benzaldehyde,2-hydroxy-5-nitro- labotest-bblt00920994 5-nitrosalicylaldehyde 5-Nitrososalicylaldehyde 5NSA 2-formyl-4-nitrophenolate

Molecular Formula: C7H5NO4

Molecular Weight: 167.12

MDL Number: MFCD00007337

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

Product Description:

2-Hydroxy-5-nitrobenzaldehyde is a substituted salicylaldehyde derivative featuring a hydroxyl group at the 2-position and a nitro group at the 5-position on the benzene ring. Its molecular formula is C7H5NO4, and it appears as a yellow to brown crystalline powder. This compound serves as a key building block in organic synthesis, particularly for constructing heterocyclic systems. It is widely used as an intermediate in the pharmaceutical industry for the synthesis of various bioactive molecules, including Schiff base ligands, metal complexes, and potential drug candidates with antimicrobial or anticancer activities. Its aldehyde and phenolic hydroxyl groups enable versatile condensation and chelation reactions. Additionally, it functions as a general synthetic building block for preparing fine chemicals and specialty materials. Due to its reactive aldehyde group, it is commonly employed in condensation reactions, such as the formation of hydrazones or imines, making it a valuable reagent in both medicinal chemistry and synthetic organic chemistry research.

Physical Properties

Melting Point: 125-128 °C(lit.)

Boiling Point: 300.2 °C at 760 mmHg

Flash Point: 137.3 °C

Density: 1.5 g/cm3

Analytical Data

Appearance: yellow to brown crystals or powder