BOC-D-SER-OME, CAS No. 95715-85-8

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95715-85-8

Catalog No. EBD2203059

CAS 95715-85-8

Name BOC-D-SER-OME

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Basic Information

Synonyms: D-Serine,N-[(1,1-dimethylethoxy)carbonyl]-,methylester n-(tert-butoxycarbonyl)-d-serinemethylester d-serine,n-[(1,1-dimethylethoxy)carbonyl]-,methylester(9ci) n-(tert-bbutoxycarbonyl)-l-serinemethylester boc-d-serinemethylesteroil n-boc-d-serinemethylester n-boc-d-ser-methylester

Molecular Formula: C9H17NO5

Molecular Weight: 219.23

MDL Number: MFCD00270516

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

N-(tert-Butoxycarbonyl)-D-serine methyl ester is a chiral, protected amino acid derivative. It features a tert-butoxycarbonyl (Boc) protecting group on the amine functionality and a methyl ester on the carboxylic acid group of D-serine. This compound is a white to off-white crystalline powder. This molecule is a crucial chiral building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key intermediate in the solid-phase and solution-phase synthesis of peptides and peptidomimetics. The Boc-protected D-serine derivative is essential for introducing the D-serine residue into peptide sequences, which is important for modulating biological activity, stability, and conformation of therapeutic peptides. It is widely used in the research and development of various bioactive compounds. The compound is sensitive to strong acids, which remove the Boc protecting group. It should be stored in a cool, dry place, and handled with standard laboratory safety precautions, including the use of personal protective equipment.

Physical Properties

Boiling Point: 215 °C(lit.)

Flash Point: 113 °C

Density: 1.08 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.453(lit.)

Storage: Store at 0-5°C

Analytical Data

Appearance: colorless to light yellow liquid