(R)-4-Isopropyloxazolidin-2-one, CAS No. 95530-58-8

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

95530-58-8

Catalog No. EBD48887

CAS 95530-58-8

Name (R)-4-Isopropyloxazolidin-2-one

Get Quote

Basic Information

Synonyms: (R)-4-Isopropyl-2-oxazolidinone (4R)-4-(propan-2-yl)-1,3-oxazolidin-2-one (R)-(+)-4-Isopropyl-2-Oxazolidinone 2-oxazolidinone,4-(1-Methylethyl)-,(4R)- (4r)-4-isopropyl-1,3-oxazolidin-2-one (4r)-(+)-isopropyl-2-oxazolidinone 4-r-isopropyl-oxazolidin-2-one (r)-(+)-4-isopropyl-2-oxazolidinone,99%(99%ee/glc) (r)-isopropyloxazolidinone (R)-4-Isopropyloxazolidin-2-one

Molecular Formula: C6H11NO2

Molecular Weight: 129.16

MDL Number: MFCD00075172

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

(4R)-(+)-4-Isopropyl-2-oxazolidinone is a chiral oxazolidinone derivative. It is a white to off-white crystalline solid with the molecular formula C6H11NO2. This compound is a key member of the Evans auxiliary family, specifically known as the "Evans oxazolidinone" auxiliary, which is widely recognized for its role in asymmetric synthesis. Its primary and most significant application is as a chiral auxiliary in organic synthesis, particularly in the enantioselective alkylation, aldol, and Diels-Alder reactions. It is extensively used in the pharmaceutical industry for the synthesis of chiral drug intermediates and active pharmaceutical ingredients (APIs). The compound's ability to induce high stereoselectivity makes it invaluable for constructing complex molecules with defined stereocenters, a critical requirement in modern drug development. Beyond its role as a chiral auxiliary, it also serves as a versatile chiral building block. Its structural framework is incorporated into more complex molecular architectures. Due to its specific and advanced synthetic utility, it is primarily categorized as a pharmaceutical intermediate rather than a general-purpose reagent.

Physical Properties

Melting Point: 70-72 °C(lit.)

Boiling Point: 291.1 °C at 760 mmHg

Flash Point: 129.9 °C

Density: 1.038 g/cm3

Solubility: Soluble

Storage: 0-6°C

Analytical Data

Appearance: white to light yellow crystal powder