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    953780-78-4

    Catalog No. EBD1614781

    CAS 953780-78-4

    Name (R)-3-Methylmorpholine hydrochloride

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    Basic Information

    Synonyms: (R)-3-Methylmorpholinehydrochloride

    Molecular Formula: C5H12ClNO

    Molecular Weight: 137.61

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-3-Methylmorpholine hydrochloride is a chiral amine compound featuring a morpholine ring substituted with a methyl group at the 3-position. It is commonly supplied as a hydrochloride salt to enhance its stability and handling properties. The compound is characterized by its specific (R)-enantiomeric configuration, which is crucial for applications in asymmetric synthesis and pharmaceutical development. This chiral building block serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its primary application is in the preparation of drugs targeting the central nervous system, such as certain antidepressants and antipsychotics. The (R)-3-methylmorpholine scaffold is a valuable structural motif for introducing chirality and modulating the biological activity and pharmacokinetic profiles of final drug molecules. It is frequently utilized in medicinal chemistry research and process development for constructing complex, enantiomerically pure targets. As a versatile chiral amine, it is also employed in organic synthesis as a ligand or auxiliary in catalytic asymmetric reactions. Its stability as a salt form makes it a practical reagent for laboratory and industrial-scale processes.
    Physical Properties

    Storage: −20°C

    mg g kg ml l t