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    952423-57-3

    Catalog No. EBD3327503

    CAS 952423-57-3

    Name benzyl 3-formyl-8-azabicyclo[3.2.1]octane-8-carboxylate

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    Basic Information

    Synonyms: (3-外型)-苄基-3-甲酰基-8-氮杂双环[3.2.1]辛烷-8-羧酸酯 (3-外型)-苄基-3-甲酰基-8-氮杂双环[3.2.1]辛烷-8-羧酸酯

    Molecular Formula: C16H19NO3

    Molecular Weight: 273.33

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (3-endo)-Benzyl 3-formyl-8-azabicyclo[3.2.1]octane-8-carboxylate is a bicyclic amine derivative featuring a tropane-like 8-azabicyclo[3.2.1]octane scaffold. This structure incorporates both a formyl group and a benzyloxycarbonyl (Cbz) protecting group on the nitrogen atom, making it a versatile chiral building block. This compound serves as a key advanced intermediate in the synthesis of complex pharmaceutical agents. Its primary application is in the research and development of tropane alkaloid derivatives and related bioactive molecules. The protected amine and the aldehyde functionality provide handles for further chemical elaboration, allowing for the construction of diverse molecular libraries targeting neurological disorders. As a functionalized heterocyclic amine, it is a valuable synthon in medicinal chemistry for exploring structure-activity relationships. The compound is typically handled under inert conditions due to the sensitivity of the aldehyde group.
    Physical Properties

    Storage: −20°C

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