2-Methyl-2H-indazol-5-ylboronic acid, CAS No. 952319-71-0

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952319-71-0

Catalog No. EBD10017

CAS 952319-71-0

Name 2-Methyl-2H-indazol-5-ylboronic acid

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Basic Information

Synonyms: 2-methylindazole-5-boronicacid (2-methyl-2h-indazol-5-yl)boronicacid 2-methylindazol-5-yl)boronicacid 2-methyl-2h-indazole-5-boronicacid b-(2-methyl-2h-indazol-5-yl)boronicacid (2-methylindazol-5-yl)boronicacid boronicacid,B-(2-methyl-2H-indazol-5-yl)- 2-Methyl-2H-indazol-5-ylboronicacid

Molecular Formula: C8H9BN2O2

Molecular Weight: 175.98

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

Product Description:

2-Methyl-2H-indazol-5-ylboronic acid is a boronic acid derivative featuring an indazole heterocyclic core. It serves as a key synthetic intermediate in medicinal chemistry, particularly in the construction of complex molecules via Suzuki-Miyaura cross-coupling reactions. The boronic acid functional group at the 5-position allows for efficient carbon-carbon bond formation with aryl or heteroaryl halides. This compound is primarily utilized in the research and development of pharmaceutical agents. Its indazole scaffold is a privileged structure found in numerous bioactive molecules targeting various therapeutic areas. As a specialized heterocyclic boronic acid building block, it is instrumental in the synthesis of potential drug candidates, including kinase inhibitors and other small molecule therapeutics. While its primary identity is as a pharmaceutical intermediate, its well-defined structure and reactivity also make it a valuable organic synthesis building block for constructing more complex chemical architectures in research settings.

Physical Properties

Boiling Point: 430.8°C at 760 mmHg

Flash Point: 214.3°C

Density: 1.27g/cm3