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    951163-61-4

    Catalog No. EBD8135

    CAS 951163-61-4

    Name Carbamic acid, N-[(3S,5S)-5-methyl-3-piperidinyl]-, 1,1-dimethylethyl ester

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    Basic Information

    Synonyms: Carbamicacid,N-[(3S,5S)-5-methyl-3-piperidinyl]-,1,1-dimethylethylester n-[(3s,5s)-5-methyl-3-piperidinyl]carbamicacidtert-butylester n-[(3s,5s)-5-methyl-3-piperidinyl]-carbamicacid1,1-dimethylethylester tert-butyl(3s,5s)-5-methylpiperidin-3-ylcarbamate NemonoxacinIntermediate-2 1-Benzoylpiperazinehydrochloride

    Molecular Formula: C11H22N2O2

    Molecular Weight: 214.3

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    The compound with CAS number 951163-61-4 is a chiral piperidine derivative, specifically N-[(3S,5S)-5-methyl-3-piperidinyl]-carbamic acid 1,1-dimethylethyl ester. Its structure features a tert-butyloxycarbonyl (Boc) protected amine group on a substituted piperidine ring, which is a common motif in medicinal chemistry. This compound is primarily utilized as a key chiral intermediate in the synthesis of pharmaceutical active ingredients. Its specific stereochemistry ((3S,5S)-configuration) is crucial for the biological activity of the final drug molecule. It is notably referenced in the synthesis of advanced drug candidates, particularly those targeting the central nervous system (CNS) or other therapeutic areas where chiral amines are pivotal pharmacophores. As a Boc-protected amine, it serves as a versatile building block, allowing for selective deprotection and further functionalization under mild acidic conditions. This makes it a valuable synthon for constructing complex molecules in drug discovery and process chemistry.
    Physical Properties
    mg g kg ml l t