4-amino-L-phenylalanine, CAS No. 943-80-6

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943-80-6

Catalog No. EBD2224411

CAS 943-80-6

Name 4-amino-L-phenylalanine

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Basic Information

Synonyms: 4-H2N-L-Phe 4-amino-L-phenylalanine l-4-aminophe l-4-aminophenylalanine l-4-aminophenylalaninedihydrochloride h-phe(p-nh2)-oh2hcl h-phe(4-nh2)-oh h-phe(4-nh2)-oh2hcl h-p-amino-l-phe-oh l-p-aminophenylalanine2hcl P-amino-L-phenylalanine H-p-Amino-Phe-OH.HCl H-Phe(4-NH?)-OH l-3-(4-aminophenyl)alanine

Molecular Formula: C9H12N2O2

Molecular Weight: 180.2

MDL Number: MFCD00069926

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

4-Amino-L-phenylalanine is a non-proteinogenic aromatic amino acid derivative. It features a phenylalanine backbone with an additional amino group substituted at the para-position of the phenyl ring. This structural modification imparts unique chemical and biological properties compared to the canonical amino acid. This compound serves as a crucial building block in medicinal chemistry and peptide research. Its primary application is as a synthetic intermediate for the preparation of peptide-based drugs and bioactive molecules. The para-amino group provides a versatile handle for further chemical modifications, such as conjugation with fluorescent dyes, biotin, or other functional groups, enabling the creation of labeled peptides or probes for biochemical studies. It is also investigated for its potential incorporation into peptides to modulate their stability, receptor binding affinity, or pharmacokinetic properties. As a specialty amino acid derivative, it is primarily used in research and development settings rather than as a bulk commodity. Handling requires standard precautions for laboratory chemicals.

Physical Properties

Boiling Point: 383.5 °C at 760 mmHg

Flash Point: 185.8 °C

Density: 1.289 g/cm3

Solubility: slightly soluble in water

Storage: 2-8°C

Analytical Data

Appearance: white needle crystal