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    941-91-3

    Catalog No. EBD170644

    CAS 941-91-3

    Name 3-bromo-1-methylquinolin-2-one

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    Basic Information

    Synonyms: 3-bromo-1-methylquinolin-2(1H)-one 2(1H)-quinolinone,3-bromo-1-methyl- 3-bromo-1-methyl-1,2-dihydroquinolin-2-one 3-bromo-1-methyl-1h-quinolin-2-one n-methyl-3-bromo-2(1h)-quinolinone 3-bromo-1-methyl-quinolin-2-one 3-bromo-1-methylquinolin-2-one

    Molecular Formula: C10H8BrNO

    Molecular Weight: 238.08

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    3-Bromo-1-methylquinolin-2(1H)-one is a heterocyclic organic compound featuring a quinolin-2-one core substituted with a bromine atom at the 3-position and a methyl group on the nitrogen atom. It serves as a versatile and valuable synthetic building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various biologically active molecules, particularly in the development of pharmaceutical candidates. The bromine atom at the 3-position is a reactive site amenable to cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), allowing for the introduction of diverse substituents to explore structure-activity relationships. The quinolin-2-one scaffold is a privileged structure found in compounds with a range of therapeutic activities. This compound is commercially available from suppliers specializing in fine chemicals and advanced intermediates for drug discovery. It is typically handled with standard precautions for halogenated organic compounds in a well-ventilated laboratory environment.
    Physical Properties

    Boiling Point: 299.5 °C at 760 mmHg

    Flash Point: 134.9 °C

    Density: 1.592 g/cm3

    mg g kg ml l t