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    938462-28-3

    Catalog No. EBD2222240

    CAS 938462-28-3

    Name (bS)-b-amino-3-chloro- Benzenepropanol

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    Basic Information

    Synonyms: Benzenepropanol,β-amino-3-chloro-,(βS)-

    Molecular Formula: C9H12ClNO

    Molecular Weight: 185.65

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-3-Amino-3-(3-chlorophenyl)propan-1-ol is a chiral amino alcohol derivative characterized by a 3-chlorophenyl group and a primary amine functionality separated by a propanol linker. It serves as a key chiral building block in pharmaceutical synthesis. Its primary application is as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly serotonin-norepinephrine reuptake inhibitors (SNRIs) like levomilnacipran. The (S)-enantiomer is essential for imparting the desired biological activity. The compound's structure, featuring both a nucleophilic amine and a hydroxyl group, makes it a versatile synthon for constructing complex molecules in medicinal chemistry. This compound is typically handled under inert atmosphere due to its sensitivity. It is commercially available for research and development purposes in the pharmaceutical industry.
    Physical Properties
    mg g kg ml l t