5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one, CAS No. 93609-84-8

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93609-84-8

Catalog No. EBD1094810

CAS 93609-84-8

Name 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one

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Basic Information

Synonyms: 2(1H)-Quinolinone,5-acetyl-8-(phenylmethoxy)- 8-(Benzyloxy)-5-(1-oxoethyl)-1H-quinolin-2-one 5-Acetyl-8-benzyloxy-1H-quinolin-2-one IndacaterolIntermediate-1 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one

Molecular Formula: C18H15NO3

Molecular Weight: 293.32

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

Product Description:

5-Acetyl-8-benzyloxy-1H-quinolin-2-one is a heterocyclic organic compound featuring a quinolin-2-one core structure substituted with an acetyl group at the 5-position and a benzyloxy group at the 8-position. It serves as a key synthetic intermediate in medicinal chemistry research. Its primary application is in the synthesis of biologically active molecules, particularly in the development of potential pharmaceutical agents. The compound's structure, containing both a reactive ketone and a protected phenolic hydroxyl group, makes it a versatile building block for constructing more complex heterocyclic systems. It has been specifically cited in patent literature related to the synthesis of compounds with potential therapeutic activities. As a specialized intermediate, it is not a commodity chemical but is utilized in research-scale synthesis for lead optimization and structure-activity relationship (SAR) studies.

Physical Properties

Melting Point: 174-176 °C

Boiling Point: 569.179 °C at 760 mmHg

Flash Point: 298.029 °C

Density: 1.231 g/cm3