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    93601-86-6

    Catalog No. EBD12397

    CAS 93601-86-6

    Name (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride

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    Basic Information

    Synonyms: N-(2-Chloro-4,6-dimethylphenyl)acetamide

    Molecular Formula: C14H22ClNO

    Molecular Weight: 255.78

    MDL Number: MFCD10567061

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthylamine hydrochloride is a chiral amine derivative with a tetrahydro-naphthalene core structure. It is a key synthetic intermediate in the production of the pharmaceutical agent Rotigotine. This compound is primarily used in the synthesis of Rotigotine, a non-ergoline dopamine agonist. Rotigotine is an active pharmaceutical ingredient (API) used in the treatment of Parkinson's disease and restless legs syndrome. The (S)-enantiomer is crucial for the biological activity of the final drug product. As a chiral intermediate, its synthesis and purification are critical steps in ensuring the enantiomeric purity of the final API. The compound is typically handled under controlled conditions in pharmaceutical manufacturing settings.
    Physical Properties
    mg g kg ml l t