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    920274-04-0

    Catalog No. EBD8102

    CAS 920274-04-0

    Name (S)-2-(3-Fluorophenyl)pyrrolidine

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    Basic Information

    Synonyms: (S)-2-(3-fluorophenyl)pyrrolidine (2s)-2-(3-fluorophenyl)pyrrolidine pyrrolidine,2-(3-fluorophenyl)-,(2s)-

    Molecular Formula: C10H12FN

    Molecular Weight: 165.21

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-2-(3-Fluorophenyl)pyrrolidine is a chiral, fluorinated heterocyclic amine. It features a pyrrolidine ring substituted at the 2-position with a 3-fluorophenyl group, and the stereocenter at this position is in the (S) configuration. This specific stereochemistry is often critical for its biological activity and interaction with target receptors. This compound is primarily utilized as a key chiral intermediate or building block in pharmaceutical research and development. Its structure, combining a basic amine moiety within a constrained pyrrolidine ring and a fluorinated aromatic system, makes it a valuable scaffold for constructing drug candidates, particularly those targeting the central nervous system (CNS). The fluorine atom can enhance metabolic stability and influence binding affinity. As a versatile synthetic building block, it is employed in medicinal chemistry for the synthesis of more complex molecules. Its applications are driven by the need for enantiomerically pure intermediates in the production of potential therapeutic agents.
    Physical Properties

    Boiling Point: 232.3 °C at 760 mmHg

    Flash Point: 94.3 °C

    Density: 1.078 g/cm3

    mg g kg ml l t