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    913613-82-8

    Catalog No. EBD3073222

    CAS 913613-82-8

    Name 2(1H)-QUINOLINONE,7-(4-CHLOROBUTOXY)-

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    Basic Information

    Synonyms: 7-(4-chlorobutoxy)-1h-quinolin-2-one 7-(4-chlorobutoxy)quinolin-2(1h)-one 2(1H)-QUINOLINONE,7-(4-CHLOROBUTOXY)-

    Molecular Formula: C13H14ClNO2

    Molecular Weight: 251.71

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    7-(4-Chlorobutoxy)-2(1H)-quinolinone is a synthetic organic compound featuring a quinolinone core substituted with a 4-chlorobutoxy group at the 7-position. It is a key chemical intermediate in the synthesis of more complex bioactive molecules. This compound is primarily utilized in pharmaceutical research and development. It serves as a crucial building block for the synthesis of potent and selective phosphodiesterase 10A (PDE10A) inhibitors. PDE10A is an enzyme highly expressed in the striatum of the brain, making it a promising therapeutic target for central nervous system disorders such as schizophrenia and Huntington's disease. The quinolinone scaffold and the chlorobutoxy side chain are essential structural components for achieving the desired biological activity and pharmacokinetic properties in these drug candidates. As a specialized intermediate, its use is confined to advanced organic synthesis within medicinal chemistry programs. Proper handling is required due to its reactive functional groups and potential toxicity associated with intermediates in drug synthesis.
    Physical Properties
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