7-Hydroxy-4-methylcoumarin, CAS No. 90-33-5

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90-33-5

Catalog No. EBD968954

CAS 90-33-5

Name 7-Hydroxy-4-methylcoumarin

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Basic Information

Synonyms: 4-MU Hymecromone Coumarin4 4-Methyl-7-hydroxycoumarin 7-hydroxy-4-methyl-2,h-1-benzo-pyran-2-one 7-hydroxy-4-methyl-2-oxo-3-chromene 7-hydroxy-4-methylbenzpyrone bilcolic bilicante beta-methylumbelliferone cantabilin eurogae imechromone medilla 4-Methylumbelliferone 2H-1-Benzopyran,7-hydroxy-4-methyl-2-oxo- 7-hydroxy-4-methyl-2h-1-benzopyren-2-on Hymecromon 7-Hydroxy-4-methylcoumarin

Molecular Formula: C10H8O3

Molecular Weight: 176.17

MDL Number: MFCD00006866

Categories: Materials Chemistry > Optoelectronic and Organic Semiconductor Materials > Dye Precursors Medicinal Chemistry > APIs and Their Salts > Digestive System Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

7-Hydroxy-4-methylcoumarin is a synthetic coumarin derivative featuring a benzopyrone core with a hydroxyl group at the 7-position and a methyl group at the 4-position. It exhibits strong blue fluorescence under UV light, making it a widely used fluorophore in biochemical assays, including enzyme activity detection (e.g., for esterases and phosphatases) and as a fluorescent labeling reagent. In pharmaceutical contexts, it serves as an active pharmaceutical ingredient (API) in choleretic and antispasmodic drugs, primarily used to treat biliary tract disorders. Its photophysical properties also enable its application in laser dyes and optical brighteners.

Physical Properties

Color: off-white to yellow

Melting Point: 188.5-190 °C(lit.)

Boiling Point: 377.4 °C at 760 mmHg

Flash Point: 174.5 °C

Density: 1.319 g/cm3

Solubility: slightly soluble

Analytical Data

Appearance: off-white to yellow crystals