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    89889-51-0

    Catalog No. EBD3317408

    CAS 89889-51-0

    Name (+)-Biotin-LC-LC

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    Basic Information

    Synonyms: Biotin-C5-amino-C5-amino (+)-Biotin-LC-LC 6-{[6-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoyl]amino}hexanoicacid LC-LC-(+)-Biotin

    Molecular Formula: C23H40N4O5

    Molecular Weight: 452.59

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    (+)-Biotin-LC-LC is a biotin derivative featuring an extended linker structure. The "LC-LC" designation refers to two long-chain (aminocaproyl) spacers, which significantly increase the distance between the biotin moiety and any conjugated molecule or surface. This extended linker provides greater flexibility and accessibility, reducing steric hindrance in binding interactions. This compound is primarily used as a critical reagent in life science research and biotechnology. Its main application is in affinity-based purification and detection systems, where it serves as a high-efficiency biotinylation agent for proteins, antibodies, and other biomolecules. The biotin tag allows for strong and specific capture by streptavidin or avidin, which are immobilized on resins, beads, or plates. The long spacer arms are particularly advantageous for labeling large proteins or when the biotin binding site might be partially obscured, ensuring optimal interaction with streptavidin. It is also utilized in the development of targeted probes and in some advanced therapeutic modalities, such as the construction of biotinylated ligands for proximity-based systems. The product is typically supplied as a solid and should be stored under appropriate conditions to maintain stability. As with many biotin derivatives, it is designed for research use in molecular biology, biochemistry, and diagnostic assay development.
    Physical Properties

    Boiling Point: 857.3°C at 760 mmHg

    Flash Point: 472.3°C

    Density: 1.168g/cm3

    mg g kg ml l t