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    89794-02-5

    Catalog No. EBD44579

    CAS 89794-02-5

    Name 4-Bromo-2-chlorotoluene

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    Basic Information

    Synonyms: 4-Bromo-2-chloro-1-methylbenzene Benzene,4-bromo-2-chloro-1-methyl- 4-bromo-2-chlorotoluene,98% 4-Bromo-2-chlorotoluene 1-bromo-3-chloro-4-methylbenzene toluene,4-bromo-2-chloro-(6ci,7ci)

    Molecular Formula: C7H6BrCl

    Molecular Weight: 205.48

    MDL Number: MFCD00060651

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates

    Product Description:
    4-Bromo-2-chlorotoluene is an organic compound with the molecular formula C7H6BrCl. It is a halogenated aromatic compound featuring both bromine and chlorine substituents on the toluene ring, specifically at the 4- and 2- positions relative to the methyl group. This structure makes it a versatile and valuable bifunctional building block in synthetic chemistry. Its primary application is as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical industries. The presence of two different halogen atoms (bromine and chlorine) allows for selective and sequential functionalization via various cross-coupling reactions (e.g., Suzuki, Negishi) or nucleophilic substitutions. It is frequently used in the preparation of active pharmaceutical ingredients (APIs) and other fine chemicals where a substituted toluene scaffold is required. As a halogenated compound, it requires careful handling. It is typically a liquid at room temperature and should be stored in a cool, dry place away from strong oxidizing agents. Its reactivity profile makes it a staple reagent in research and development laboratories focused on medicinal chemistry and material science.
    Physical Properties

    Boiling Point: 212 °C(lit.)

    Flash Point: 104 °C

    Density: 1.54 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.574(lit.)

    Analytical Data

    Appearance: Clear pale yellow liquid

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