(S)-2-Hydroxypropanamide, CAS No. 89673-71-2

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89673-71-2

Catalog No. EBD2216593

CAS 89673-71-2

Name (S)-2-Hydroxypropanamide

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Basic Information

Synonyms: (S)-2-Hydroxypropanamide 2-hydroxypropionicacidamide l-(-)-lactamide (s)-(-)-lactamide (s)-(-)-2-hydroxypropionamide (s)-(-)-2-hydroxypropionamide[(s)-(-)-lactamide] (s)-(-)-lactamide,98% (s)-(-)-lactamide(s)-(-)-2-hydroxypropionamide lactamide 2-Hydroxypropionamide (2S)-2-Hydroxypropionamide=Lactamide 2-hydroxypropanamide (2S)-2-hydroxypropanamide propanamide,2-hydroxy-,(2S)- (-)-lactamide (s)-lactamide propanamide,2-hydroxy-,(s)-

Molecular Formula: C3H7NO2

Molecular Weight: 8909.0

MDL Number: MFCD00198010

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(S)-(-)-2-Hydroxypropanamide is a chiral organic compound featuring a secondary amide group and a hydroxyl group on the same carbon atom. It is a white to off-white crystalline powder. Its molecular structure, containing both a chiral center and functional groups amenable to further chemical modification, makes it a valuable building block. This compound serves as a key chiral intermediate in the synthesis of various pharmaceutical agents. Its primary application is in the production of (S)-oxybutynin, a pharmacologically active enantiomer used in the treatment of overactive bladder and urinary incontinence. The (S)-configuration is crucial for the desired biological activity. As a versatile chiral synthon, it is also employed in organic synthesis for constructing more complex molecules, particularly those requiring the introduction of a chiral hydroxyamide moiety. Its utility extends to research in medicinal chemistry for developing new drug candidates.

Physical Properties

Melting Point: 53-55 °C(lit.)

Boiling Point: 281.9°C at 760 mmHg

Flash Point: 124.3°C

Density: 1.161g/cm3