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    892874-34-9

    Catalog No. EBD2081675

    CAS 892874-34-9

    Name 7-Bromoquinoline-3-carboxylic acid

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    Basic Information

    Synonyms: 7-bromanylquinoline-3-carboxylicacid 7-bromoquinoline-3-carboxylicacid,>=98% 7-Bromoquinoline-3-carboxylicacid

    Molecular Formula: C10H6BrNO2

    Molecular Weight: 252.06

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    7-Bromoquinoline-3-carboxylic acid is an organic compound featuring a quinoline core substituted with a bromine atom at the 7-position and a carboxylic acid group at the 3-position. This structure makes it a versatile bifunctional building block, combining the reactivity of an aryl bromide and a carboxylic acid. Its primary application is as a key pharmaceutical intermediate in medicinal chemistry research and drug development. The bromine atom serves as a handle for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the carboxylic acid can be readily converted to amides, esters, or other derivatives. This allows for the efficient synthesis of diverse compound libraries based on the quinoline scaffold, which is a privileged structure found in many bioactive molecules. As a halogenated heterocyclic carboxylic acid, it is also a valuable organic synthesis building block in academic and industrial laboratories for constructing more complex molecular architectures.
    Physical Properties

    Boiling Point: 403.1°C at 760 mmHg

    Flash Point: 197.6°C

    Density: 1.732g/cm3

    mg g kg ml l t