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    886061-27-4

    Catalog No. EBD48301

    CAS 886061-27-4

    Name (S)-3-Amino-3-(4-methoxyphenyl)propan-1-ol

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    Basic Information

    Synonyms: (S)-3-Amino-3-(4-methoxyphenyl)propan-1-ol (3S)-3-Amino-3-(4-methoxyphenyl)propan-1-ol Benzenepropanol,gamma-amino-4-methoxy-,(gammaS)-

    Molecular Formula: C10H15NO2

    Molecular Weight: 181.23

    MDL Number: MFCD07784113

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    (S)-3-Amino-3-(4-methoxyphenyl)propan-1-ol is a chiral amino alcohol derivative characterized by a 4-methoxyphenyl group and a primary amino group separated by a three-carbon chain with a terminal hydroxyl group. Its specific (S)-configuration is crucial for its biological activity and utility in asymmetric synthesis. This compound serves as a key chiral building block in pharmaceutical research and development. It is notably utilized as a critical intermediate in the synthesis of (S)-Dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI) approved for the treatment of premature ejaculation. The chiral integrity of this intermediate is essential for producing the pharmacologically active enantiomer of the final API. The molecule's structure, featuring both amino and hydroxyl functional groups, makes it amenable to further chemical modifications. Its synthesis and application are subjects of patents and research focused on efficient, stereoselective routes for producing high-purity material suitable for GMP manufacturing processes in the pharmaceutical industry.
    Physical Properties
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