6-Indazolyboronic acid, CAS No. 885068-10-0

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885068-10-0

Catalog No. EBD48466

CAS 885068-10-0

Name 6-Indazolyboronic acid

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Basic Information

Synonyms: 1H-indazol-6-yl-6-boronic acid 1H-Indazole-6-boronicacid 6-Indazolyboronicacid 1H-indazol-6-ylboronicacid (1H-indazol-6-yl)boronicacid 1h-indazol-6-yl-6-boronicacid 6-(1h)indazoleboronicacid 6-indazolylboronicacid boronicacid,b-1h-indazol-6-yl- 6-indazolboronicacid indazole-6-boronicacid

Molecular Formula: C7H7BN2O2

Molecular Weight: 161.95

MDL Number: MFCD04972419

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

Product Description:

6-Indazoleboronic acid is an organic compound featuring an indazole heterocycle substituted with a boronic acid group at the 6-position. It is a white to off-white solid powder. As a boronic acid derivative, it is a key reagent in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds in organic synthesis. Its primary application is as a versatile building block in medicinal chemistry and pharmaceutical research. The indazole scaffold is a privileged structure found in numerous bioactive molecules. Therefore, 6-indazoleboronic acid is extensively used in the synthesis of potential drug candidates, particularly serving as a crucial intermediate for the construction of complex heterocyclic compounds targeting various therapeutic areas. This compound should be stored under inert conditions, protected from moisture, as boronic acids can be sensitive to hydrolysis. It is commonly used in research and development settings for the synthesis of novel chemical entities.

Physical Properties

Melting Point: 112-117 °C

Boiling Point: 457.012 °C at 760 mmHg

Flash Point: 230.193 °C

Density: 1.423 g/cm3

Storage: 2-8°C