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    882033-66-1

    Catalog No. EBD32380

    CAS 882033-66-1

    Name 4-Chloro-5-fluoro-7-azaindole

    Purity ≥95%

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    Basic Information

    Synonyms: 1H-Pyrrolo[2,3-b]pyridine,4-chloro-5-fluoro- 4-chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine 4-Chloro-5-fluoro-7-azaindole

    Molecular Formula: C7H4ClFN2

    Molecular Weight: 170.57

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Small Molecule Drug Fragments

    Product Description:
    4-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine is a heterocyclic compound featuring a fused pyrrole-pyridine core (7-azaindole) with chlorine and fluorine substituents at the 4- and 5-positions, respectively. This structure is a key building block in medicinal chemistry, particularly for the synthesis of kinase inhibitors targeting cancer and inflammatory diseases. The 7-azaindole scaffold mimics the adenine ring of ATP, enabling selective binding to kinase active sites, while the halogen atoms serve as handles for further functionalization via cross-coupling reactions. It is widely used as a small-molecule drug fragment in early-stage drug discovery and lead optimization.
    Physical Properties
    Analytical Data

    Purity: ≥95%

    mg g kg ml l t