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    881-07-2

    Catalog No. EBD73598

    CAS 881-07-2

    Name 2-methyl-8-nitroquinoline

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    Basic Information

    Synonyms: 8-Nitroquinaldine Nitroquinaldine 2-Methyl-8-nitroquinoline 2-methyl-8-nitro-quinoline

    Molecular Formula: C10H8N2O2

    Molecular Weight: 188.18

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    8-Nitroquinaldine is an organic compound with the molecular formula C10H8N2O2. It is a nitro-substituted derivative of quinaldine (2-methylquinoline), featuring a nitro group at the 8-position of the quinoline ring system. This structure makes it a versatile heterocyclic building block. Its primary application is in pharmaceutical research and development as a key synthetic intermediate. The nitro group serves as a versatile functional handle that can be readily reduced to an amino group, enabling the synthesis of various 8-aminoquinaldine derivatives. These derivatives are important scaffolds for developing compounds with potential biological activities, including antimicrobial and anticancer agents. As a nitroaromatic compound, 8-nitroquinaldine requires careful handling due to potential irritant properties. It is primarily used in laboratory-scale organic synthesis and is valued for its role in constructing complex nitrogen-containing heterocycles relevant to medicinal chemistry.
    Physical Properties

    Melting Point: 138°C

    mg g kg ml l t