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    88-68-6

    Catalog No. EBD54396

    CAS 88-68-6

    Name 2-Aminobenzamide

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    Basic Information

    Synonyms: Anthranilamide 2-Aminobenzamide,(Anthranilamide) ATA Anthranilicacidamide 2-Aminobenzamide O-Aminobenzamide

    Molecular Formula: C7H8N2O

    Molecular Weight: 136.15

    MDL Number: MFCD00007981

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    2-Aminobenzamide is an organic compound featuring both an amine and an amide group on an aromatic benzene ring. It serves as a versatile and important building block in organic synthesis, particularly for the construction of nitrogen-containing heterocycles. Its primary industrial application is as a key pharmaceutical intermediate. It is a crucial precursor in the synthesis of various bioactive molecules, most notably quinazolinone derivatives. These quinazolinone scaffolds are found in numerous drugs with diverse therapeutic activities, including anticancer, antimicrobial, anti-inflammatory, and anticonvulsant agents. The compound's structure allows for facile cyclization reactions to form these privileged heterocyclic systems. Beyond its role in medicinal chemistry, 2-aminobenzamide is also utilized in materials science and as a ligand in coordination chemistry. It is commercially available and commonly employed in research laboratories for the development of new chemical entities.
    Physical Properties

    Melting Point: 111-113 °C(lit.)

    Boiling Point: 300 °C

    Flash Point: 198 °C

    Density: 1.233 g/cm3

    Analytical Data

    Appearance: light brown to grey-brown crystal powder or flakes

    mg g kg ml l t