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    877773-30-3

    Catalog No. EBD2210391

    CAS 877773-30-3

    Name (2S,6S)-2,6-Dibenzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole

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    Basic Information

    Synonyms: (2S,6S)-2,6-Dibenzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole (2S,6S)-2,6-Di-benzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole

    Molecular Formula: C19H21N3

    Molecular Weight: 291.39

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (2S,6s)-2,6-Dibenzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole is a chiral bicyclic diamine compound featuring a fused imidazo[1,2-a]imidazole core structure. It is characterized by its two benzyl substituents and the specific (2S,6s) stereochemistry, which is crucial for its function as a chiral ligand or organocatalyst precursor. This compound is primarily utilized as a key chiral intermediate or a precursor for the synthesis of organocatalysts, particularly in the development of novel chiral guanidine derivatives. Its rigid, bicyclic framework and the presence of multiple nitrogen atoms make it a valuable scaffold for constructing highly enantioselective catalysts used in asymmetric synthesis, such as in Michael additions and other carbon-carbon bond-forming reactions relevant to pharmaceutical manufacturing. While its direct, specific API application is not widely documented, its role is firmly established in advanced medicinal chemistry research for creating chiral building blocks and catalytic systems. It represents a specialized synthetic tool rather than a commodity chemical.
    Physical Properties

    Boiling Point: 436.111 °C at 760 mmHg

    Flash Point: 217.553 °C

    Density: 1.191 g/cm3

    mg g kg ml l t