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    876367-84-9

    Catalog No. EBD36626

    CAS 876367-84-9

    Name cis-3,5-Piperidinedicarboxylic acid

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    Basic Information

    Synonyms: 2-Bromo-5H-pyrrolo[2,3-b]pyrazine cis-3,5-Piperidinedicarboxylicacid 2,3-o-(r)-isopropylidene-d-glycerol cis-piperidine-3,5-dicarboxylicacid

    Molecular Formula: C7H11NO4

    Molecular Weight: 173.17

    MDL Number: MFCD09832854

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    Cis-3,5-piperidinedicarboxylic acid is a heterocyclic organic compound featuring a piperidine ring substituted with two carboxylic acid groups in a cis configuration. It serves as a versatile chiral building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of pharmaceutical compounds. The rigid, bicyclic structure derived from this scaffold is valuable for constructing molecules that interact with biological targets, particularly in the central nervous system. For instance, derivatives have been explored in the development of modulators for neurotransmitter receptors. As a bifunctional molecule containing both a secondary amine and carboxylic acids, it is also a useful synthon in organic synthesis for constructing complex, constrained architectures. It is typically handled as a solid and requires standard precautions for handling carboxylic acids.
    Physical Properties

    Boiling Point: 362.3 °C at 760 mmHg

    Flash Point: 172.9 °C

    Density: 1.363 g/cm3

    mg g kg ml l t