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    873429-57-3

    Catalog No. EBD2206085

    CAS 873429-57-3

    Name 2,3-Dichloro-L-Phenylalanine

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    Basic Information

    Synonyms: (S)-2-Amino-3-(2,3-dichlorophenyl)propanoicacid 2,3-Dichloro-L-Phenylalanine L-Phenylalanine,2,3-dichloro-

    Molecular Formula: C9H9Cl2NO2

    Molecular Weight: 234.08

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    2,3-Dichloro-L-Phenylalanine is a non-natural, chiral amino acid derivative characterized by a phenylalanine backbone substituted with chlorine atoms at the 2- and 3-positions of the aromatic ring. Its molecular formula is C9H9Cl2NO2, and it exists as the (S)-enantiomer, making it a valuable source of chirality in synthetic chemistry. This compound serves as a crucial chiral building block in pharmaceutical research and development. Its primary application is as a key intermediate in the synthesis of complex bioactive molecules, particularly in the construction of peptide-based drugs or drug candidates where the introduction of a halogenated, hydrophobic phenylalanine side chain can modulate biological activity, stability, and receptor binding affinity. The presence of the dichloro substituents significantly alters the electronic and steric properties of the aromatic ring compared to natural phenylalanine. As a specialty amino acid derivative, it is utilized in medicinal chemistry for structure-activity relationship (SAR) studies and in the preparation of potential therapeutic agents targeting various diseases. It is typically handled as a high-purity research chemical under controlled laboratory conditions.
    Physical Properties
    mg g kg ml l t