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    870195-94-1

    Catalog No. EBD953153

    CAS 870195-94-1

    Name 2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

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    Basic Information

    Synonyms: akosbrn-1130 2-chlorophenylboronicacid,pinacolester 3-hydroxy-2,3-dimethylbutan-2-ylhydrogen2-chlorophenylboronate 2-chlorobenzeneboronicacid,pinacolester

    Molecular Formula: C12H16BClO2

    Molecular Weight: 238.52

    MDL Number: MFCD05663846

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    2-Chlorophenylboronic acid pinacol ester is an organoboron compound featuring a boronic ester functional group protected by pinacol. It serves as a versatile and stable synthetic building block in organic chemistry, particularly in palladium-catalyzed cross-coupling reactions such as the Suzuki-Miyaura reaction. Its structure combines an aryl chloride moiety with the boronic ester, allowing for sequential functionalization. This compound is primarily used in the synthesis of complex molecules, including pharmaceuticals, agrochemicals, and advanced materials. The boronic ester group enables the formation of new carbon-carbon bonds with various aryl or vinyl halides, while the chlorine atom on the phenyl ring can act as a handle for further derivatization (e.g., via another cross-coupling or substitution reaction), making it a valuable bifunctional intermediate in multi-step syntheses. As a protected form of 2-chlorophenylboronic acid, it offers improved stability against protodeboronation and moisture compared to the free boronic acid, facilitating handling and storage. It is a standard reagent in research and process chemistry for constructing biaryl and other conjugated systems.
    Physical Properties

    Boiling Point: 314.949°C at 760 mmHg

    Flash Point: 144.276°C

    Density: 1.103g/cm3

    mg g kg ml l t