(S)-4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid, CAS No. 868689-63-8

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868689-63-8

Catalog No. EBD2219348

CAS 868689-63-8

Name (S)-4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid

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Basic Information

Synonyms: (S)-4-(tert-butoxycarbonyl)morpholine-2-carboxylicacid (s)-n-boc-2-morpholinecarboxylicacid (s)-4-boc-morpholine-2-carboxylicacid (s)-n-boc-morpholine-2-carboxylicacid (2s)-4-[(tert-butoxy)carbonyl]morpholine-2-carboxylicacid 868689-63-8 (s)-4-(tert-butoxycabonyl)morpholine-2-carboxylicacid (2S)-4-(tert-butoxycarbonyl)morpholine-2-carboxylicacid

Molecular Formula: C10H17NO5

Molecular Weight: 231.25

MDL Number: MFCD06200662

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid is a chiral morpholine derivative featuring both a carboxylic acid and a tert-butoxycarbonyl (Boc) protected amine group. This compound serves as a versatile and valuable chiral building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key intermediate in the synthesis of complex drug molecules. The chiral morpholine scaffold is a privileged structure found in numerous bioactive compounds and active pharmaceutical ingredients (APIs). The presence of orthogonal protecting groups (Boc and free acid) allows for selective functionalization, making it a crucial precursor for constructing peptidomimetics and other nitrogen-containing heterocycles central to medicinal chemistry. While its direct, specific drug target is not publicly disclosed in detail, its role is firmly established in the research and development pipeline for creating novel therapeutic agents. As a specialized chiral intermediate, it is not considered a generic, high-volume chemical but a high-value synthetic tool for constructing sophisticated molecular architectures.

Physical Properties

Melting Point: 127-134 °C

Boiling Point: 369.5 °C at 760 mmHg

Flash Point: 177.3 °C

Density: 1.23 g/cm3