Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    86-68-0

    Catalog No. EBD2338312

    CAS 86-68-0

    Name 6-methoxyquinoline-4-carboxylic acid

    Get Quote
    Basic Information

    Synonyms: 6-methoxyquinoline-4-carboxylicacid quininicacid

    Molecular Formula: C11H9NO3

    Molecular Weight: 203.19

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    6-Methoxyquinoline-4-carboxylic acid is an organic compound featuring a quinoline core structure substituted with a methoxy group at the 6-position and a carboxylic acid group at the 4-position. It serves as a versatile and important heterocyclic building block in medicinal chemistry. Its primary and most significant application is as a key synthetic intermediate in the production of various pharmaceutical agents. Notably, it is a crucial precursor in the synthesis of the antimalarial drug Primaquine and its derivatives. The quinoline-4-carboxylic acid scaffold is also explored in the development of other bioactive molecules, including potential antibacterial and anticancer compounds. Due to its defined heterocyclic structure and the presence of both a carboxylic acid (for amide bond formation) and a methoxy group (for further functionalization), it is also utilized as a specialized organic synthesis block in research settings to construct more complex molecular architectures.
    Physical Properties

    Boiling Point: 385.4 °C at 760 mmHg

    Flash Point: 186.9 °C

    Density: 1.325 g/cm3

    mg g kg ml l t