methyl 2-nminobutanoate hydrochloride, CAS No. 85774-09-0

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85774-09-0

Catalog No. EBD20093

CAS 85774-09-0

Name methyl 2-nminobutanoate hydrochloride

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Basic Information

Synonyms: methyld-homoalaninatehcl methyld-homoalaninatehydrochloride butanoicacid,2-amino-,methylester,hydrochloride(1:1),(2r)- d-alpha-aminobutyricacidmethylesterhydrochloride methyl(r)-2-aminobutanoatehydrochloride butanoicacid,2-amino-,methylester,hydrochloride,(2r)- (r)-2-amino-butyricacidmethylester (r)-methyl2-aminobutanoatehydrochloride methyl(2R)-2-aminobutanoatehydrochloride Methyl(2R)-2-aminobutanoatehydrochloride(1:1) (R)-2-Amino-ButyricAcidMethylEsterHydrochloride methyl2-nminobutanoatehydrochloride

Molecular Formula: C5H12ClNO2

Molecular Weight: 153.61

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Methyl (R)-2-aminobutanoate hydrochloride is a chiral amino acid ester derivative, specifically the hydrochloride salt of the methyl ester of (R)-2-aminobutyric acid. It features a primary amine and an ester functional group, with the (R)-configuration at the chiral center. This compound is a key building block in asymmetric synthesis, particularly for introducing the (R)-2-aminobutyric acid moiety into complex molecules. Its primary application is as a pharmaceutical intermediate, serving as a chiral synthon in the synthesis of various active pharmaceutical ingredients (APIs), including antiviral drugs, enzyme inhibitors, and peptide-based therapeutics. The (R)-enantiomer is often crucial for biological activity, making this compound valuable for stereoselective drug development. Additionally, it is used as a protected amino acid derivative in peptide synthesis and biochemical research. As a hydrochloride salt, it is typically a stable, crystalline solid with improved solubility in polar solvents compared to the free base. It should be stored under dry conditions to prevent hydrolysis of the ester group. Its high enantiomeric purity makes it essential for producing optically active drugs and research chemicals.

Physical Properties