N-Boc-D-2-piperidinecarboxamide, CAS No. 848488-91-5

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848488-91-5

Catalog No. EBD48859

CAS 848488-91-5

Name N-Boc-D-2-piperidinecarboxamide

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Basic Information

Synonyms: (R)-2-Carbamoyl-piperidine-1-carboxylicacidtert-butylester N-Boc-D-2-piperidinecarboxamide tert-butyl(2R)-2-carbamoylpiperidine-1-carboxylate (r)-1-boc-2-piperidinecarboxamide (r)-tert-butyl2-carbamoylpiperidine-1-carboxylate 1-piperidinecarboxylicacid,2-(aminocarbonyl)-,1,1-dimethylethylester,(2r)- (r)-1-n-boc-pipecolamide

Molecular Formula: C11H20N2O3

Molecular Weight: 228.29

MDL Number: MFCD03840195

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

N-Boc-D-2-Piperidinecarboxamide is a chiral, Boc-protected amino acid derivative. Its molecular structure features a piperidine ring, a carboxamide group, and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom. The compound is characterized by its D-configuration at the stereogenic center. This compound serves as a crucial chiral building block and intermediate in pharmaceutical research and development. Its primary application is in the synthesis of complex bioactive molecules, particularly in the construction of peptide mimetics and drug candidates that incorporate constrained, heterocyclic amino acid motifs. The Boc group is a standard protecting group in peptide synthesis, allowing for selective deprotection under mild acidic conditions. As a specialized intermediate, it is not a commodity chemical but is supplied for research purposes. It is typically handled under standard laboratory safety protocols, and its stability is maintained when stored in a cool, dry environment.

Physical Properties

Boiling Point: 384.4 °C at 760 mmHg

Flash Point: 186.3 °C

Density: 1.123 g/cm3