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    84499-77-4

    Catalog No. EBD14810

    CAS 84499-77-4

    Name 1-(4-Bromophenyl)ethylamine hydrochloride

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    Basic Information

    Synonyms: 1-(4-Bromophenyl)ethylaminehydrochloride 1-(4-bromophenyl)ethanaminehydrochloride(1:1)

    Molecular Formula: C8H11BrClN

    Molecular Weight: 236.54

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-1-(4-Bromophenyl)ethylamine hydrochloride is a chiral amine derivative characterized by a brominated phenyl ring and an ethylamine moiety. It is a white to off-white crystalline powder with the molecular formula C8H10BrN·HCl and a molecular weight of 236.53 g/mol. The compound is typically stored under inert conditions at 2-8°C. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the production of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and other therapeutic areas. The presence of the chiral center and the reactive amine and aryl bromide functional groups makes it a versatile precursor for constructing more complex molecular architectures through various coupling and derivatization reactions. As a hydrochloride salt, it offers improved stability and handling properties compared to the free base. It is commonly used in asymmetric synthesis and medicinal chemistry research for constructing pharmacologically active molecules. Standard safety precautions for handling amines and halogenated compounds should be observed.
    Physical Properties

    Boiling Point: 294.5 °C at 760 mmHg

    Flash Point: 131.9 °C

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