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    83104-87-4

    Catalog No. EBD830203

    CAS 83104-87-4

    Name (-)-3''-Me-epigallocatechin gallate

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    Basic Information

    Synonyms: (-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-3''-Me-epigallocatechingallate EGCG-3-O-(3-O-methyl)gallate (-)-3''-Me-EGCG EGCG3''Me (-)-(2R,3R)-5,7-dihydroxy-2-(3',4',5'-trihydroxy-phenyl)chroman-3-yl3'',4''-dihydroxy-5''-methoxybenzoate (-)-epigallocatechin3-O-(3'-O-methyl-gallate) (-)-epigallocatechin-3-O-(3''-O-methyl)gallate (-)-epigallocatechin3-(3''-o-methyl)gallate (-)-egcg-3''-o-me (-)-epigallocatechin3-(3''-o-methly)gallate Benzoicacid,3,4-dihydroxy-5-methoxy-,(2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-ylester Benzoicacid,3,4-dihydroxy-5-methoxy-,3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-ylester,(2R-cis)- (-)-Epigallocatechin3-O-(3-O-methylgallate) (-)-Epigallocatechin-3-(3''-O-methyl)gallate Epigallocatechin3-O-(3-O-methyl)gallate

    Molecular Formula: C23H20O11

    Molecular Weight: 472.4

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products Medicinal Chemistry > APIs and Their Salts > Antineoplastic Agents

    Product Description:
    (-)-3''-Me-epigallocatechin gallate is a methylated derivative of (-)-epigallocatechin gallate (EGCG), a major polyphenol found in green tea. This compound is characterized by the methylation of the gallate moiety at the 3''-O position, which significantly alters its physicochemical and biological properties compared to its parent molecule. Its primary research and application focus is in the field of pharmacology and nutraceuticals. Studies indicate that this methylation enhances its metabolic stability and bioavailability, making it a compound of interest for potential therapeutic development. It exhibits a range of biological activities, including potent antioxidant, anti-inflammatory, and notably, anticancer effects. Research has explored its mechanisms, which may involve the modulation of key signaling pathways, induction of apoptosis, and inhibition of angiogenesis in various cancer cell lines. Due to its natural origin and modified structure for improved pharmacokinetics, it is investigated both as a lead compound for drug discovery and as a high-purity reference standard in analytical studies of tea polyphenols and their metabolites.
    Physical Properties
    mg g kg ml l t