Pentafluorophenyl hydrazine, CAS No. 828-73-9

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828-73-9

Catalog No. EBD40982

CAS 828-73-9

Name Pentafluorophenyl hydrazine

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Basic Information

Synonyms: BRN0747800 NSC88334 Hydrazine,(pentafluorophenyl)- Pentafluorophenylhydrazine pentafluorophenyl-hydrazine 1-(2,3,4,5,6-pentafluorophenyl)hydrazine hydrazine,1-(2,3,4,5,6-pentafluorophenyl)- (perfluorophenyl)hydrazine 2,3,4,5,6-pentafluorophenylhydrazine hydrazine,(pentafluorophenyl)-(6ci,7ci,8ci,9ci)

Molecular Formula: C6H3F5N2

Molecular Weight: 198.09

MDL Number: MFCD00007574

Categories: Synthetic Chemistry > Organic Building Blocks > Oximes and Hydrazones Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

Product Description:

Pentafluorophenylhydrazine is an organofluorine compound characterized by a phenyl ring substituted with five fluorine atoms and a hydrazine (-NHNH₂) functional group. It is a versatile reagent in synthetic organic chemistry, primarily valued for its role as a building block and derivatization agent. Its most prominent application is in the synthesis of heterocyclic compounds, particularly pyrazoles and other nitrogen-containing rings, leveraging the reactivity of the hydrazine moiety. It is also widely used as a derivatization reagent in analytical chemistry, especially in gas chromatography (GC) and mass spectrometry (MS), for the analysis of carbonyl compounds (aldehydes and ketones) by forming stable hydrazone derivatives, thereby enhancing detection and quantification. As a highly fluorinated aromatic hydrazine, it must be handled with care due to its potential toxicity and reactivity. It is a specialized chemical used predominantly in research and development settings within pharmaceutical, agrochemical, and materials science for constructing complex molecular architectures.

Physical Properties

Melting Point: 74-76 °C(lit.)

Boiling Point: 117.6 °C at 760 mmHg

Flash Point: 24.9 °C

Density: 1.691 g/cm3

Analytical Data

Appearance: beige to brown crystalline powder