N-decyl-B-D-maltopyranoside, CAS No. 82494-09-5

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82494-09-5

Catalog No. EBD2218575

CAS 82494-09-5

Name N-decyl-B-D-maltopyranoside

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Basic Information

Synonyms: β-D-Glucopyranoside,decyl4-O-α-D-glucopyranosyl- N-decyl-B-D-maltopyranoside decylbeta-d-maltopyranoside decyl-beta-d-maltoside n-decyl-4-o-alpha-d-glucopyranosyl-beta-d-glucopyranoside n-decyl-beta-d-maltopyranoside n-decyl-beta-d-maltoside decyl--d-maltoside10mmsolution n-decylb-d-maltopyranoside decyl-4-o-alpha-d-glucopyranosyl-beta-d-glucopyranosi decyl4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside N-DECYL-Β-D-MALTOSIDE Decyl-4-O-ALPHA-D-glucopyranosyl-D-glucopyranoside

Molecular Formula: C22H42O11

Molecular Weight: 482.56

Categories: Medicinal Chemistry > Pharmaceutical Excipients > Surfactants, Emulsifiers, and Solubilizers Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides

Product Description:

Decyl-β-D-maltoside is a non-ionic, high-purity detergent derived from maltose. It is a glycoside consisting of a decyl (C10) alkyl chain linked to a maltose (a disaccharide of two glucose units) headgroup via a β-glycosidic bond. This structure confers excellent amphiphilic properties. Its primary and most significant application is in the field of structural biology and membrane protein research. It is widely used as a mild, non-denaturing detergent for the solubilization, purification, and stabilization of integral membrane proteins, such as G-protein coupled receptors (GPCRs) and ion channels, maintaining their native conformation and functionality for downstream analysis like crystallization and biochemical assays. It is also utilized in pharmaceutical formulations as a solubilizing agent for poorly water-soluble drugs. Decyl-β-D-maltoside is valued for its high critical micelle concentration (CMC), which facilitates easy removal via dialysis, and its low ultraviolet absorbance, making it compatible with various spectroscopic techniques. It is considered a crucial tool in life science laboratories and biopharmaceutical development.

Physical Properties

Boiling Point: 689.4 °C at 760 mmHg

Flash Point: 370.8 °C

Density: 1.32 g/cm3

Solubility: H2O: 50 mg/mL, clear

Storage: −20°C