2-amino-2'-O-methyladenosine, CAS No. 80791-87-3

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80791-87-3

Catalog No. EBD948735

CAS 80791-87-3

Name 2-amino-2'-O-methyladenosine

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Basic Information

Synonyms: 2-amino-2'-O-methyladenosine 2'-O-Methyl-2-aminoadenosine 2,6-diamino-9-(2-O-methyl-2-D-ribofuranosyl)purine 2,6-diamino-9-(2'-O-methyl-2-D-ribofuranosyl)purine 2'-O-methyl-2,6-diaminopurineriboside 2-amino-2'-o-methyl-d-adenosine 2,6-diamino-9-(2'-o-methyl-b-d-ribofuranosyl)purine Adenosine,2-amino-2'-O-methyl- 2'-O-Methyl-2,6-diaminopurine-riboside

Molecular Formula: C11H16N6O4

Molecular Weight: 296.29

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

2-Methoxy-2',6'-diaminopurine riboside is a modified nucleoside derivative. Its structure features a purine base with methoxy and amino substituents at the 2-position and amino groups at the 2' and 6' positions, respectively, linked to a ribose sugar moiety. This specific modification distinguishes it from canonical nucleosides. This compound is primarily utilized as a key intermediate in the synthesis of nucleoside analogs for pharmaceutical research. It serves as a crucial building block for developing potential antiviral and anticancer agents, where modifications to the nucleobase are explored to modulate biological activity, stability, and selectivity. Its role is firmly within the realm of medicinal chemistry and life science research. As a specialized, structurally complex nucleoside analog, it is not a general-purpose synthetic building block. Its primary value lies in its application for constructing biologically active molecules, particularly in the development of novel therapeutic candidates targeting nucleic acid metabolism.

Physical Properties

Boiling Point: 733.177 °C at 760 mmHg

Flash Point: 397.211 °C

Density: 1.983 g/cm3