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    79640-72-5

    Catalog No. EBD2215734

    CAS 79640-72-5

    Name (S)-1-tert-Butyl 5-methyl 2-aminopentanedioate

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    Basic Information

    Synonyms: (S)-1-tert-Butyl5-methyl2-aminopentanedioate L-Glutamicacid,1-(1,1-dimethylethyl)5-methylester

    Molecular Formula: C10H19NO4

    Molecular Weight: 217.26

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-1-tert-Butyl 5-methyl 2-aminopentanedioate is a chiral, bifunctional amino acid derivative. It features a primary amine group and two differentially protected carboxylate groups (a tert-butyl ester and a methyl ester) on a pentanedioic acid backbone. This specific (S)-configuration is crucial for its applications in asymmetric synthesis. This compound serves as a key chiral building block in pharmaceutical research and development. Its primary application is as a versatile intermediate for the synthesis of various biologically active molecules, particularly those containing glutamic acid or related structural motifs. The orthogonal protecting groups allow for selective deprotection and further functionalization, making it valuable for constructing complex peptide mimetics, drug candidates, and other fine chemicals where stereochemical purity is essential. As a protected form of (S)-2-aminopentanedioic acid, it is a valuable reagent in medicinal chemistry for introducing chiral centers and exploring structure-activity relationships. It is typically handled under inert atmosphere and stored at low temperatures to preserve its stability and stereochemical integrity.
    Physical Properties
    mg g kg ml l t