2-Fluoro-6-methoxyphenylboronic acid, CAS No. 78495-63-3

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

78495-63-3

Catalog No. EBD418998

CAS 78495-63-3

Name 2-Fluoro-6-methoxyphenylboronic acid

Get Quote

Basic Information

Synonyms: (2-FLUORO-6-METHOXYBENZENE)BORONICACID 2-FLUORO-6-METHOXYLPHENYLBORONICACID 2-Fluoro-6-Methoxyphenylboroni 2-Fluoro-6-methoxybenzeneboronicacid 2-Fluoro-6-methoxybenzeneboronicacid96% 3-Fluoroanisole-2-boronicacid 2-Fluoro-6-methoxyphenylboronicacid

Molecular Formula: C7H8BFO3

Molecular Weight: 169.95

MDL Number: MFCD02179483

Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

Product Description:

2-Fluoro-6-methoxybenzeneboronic acid is an organoboron compound featuring a boronic acid functional group attached to a benzene ring substituted with fluorine and methoxy groups at the ortho and meta positions, respectively. It is a white to off-white crystalline powder. This compound serves as a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. The boronic acid group enables efficient carbon-carbon bond formation with aryl or vinyl halides in the presence of a palladium catalyst. The specific substitution pattern (fluoro and methoxy) makes it a valuable intermediate for constructing complex molecules, especially in pharmaceutical research for the synthesis of drug candidates and active pharmaceutical ingredients (APIs). It is commonly used in medicinal chemistry to introduce the 2-fluoro-6-methoxyphenyl moiety into target structures. As a research chemical, it is handled under standard laboratory conditions, and its stability is typical of arylboronic acids, requiring storage in a cool, dry place.

Physical Properties

Melting Point: 120-125 °C(lit.)

Boiling Point: 303.1 °C at 760 mmHg

Flash Point: 137.1 °C

Density: 1.26 g/cm3