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    77211-75-7

    Catalog No. EBD1121212

    CAS 77211-75-7

    Name benzyl 1-oxa-6-aza-spiro[2.5]octane-6-carboxylate

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    Basic Information

    Synonyms: benzyl1-oxa-6-aza-spiro[2.5]octane-6-carboxylate 1-oxa-6-aza-spiro[2.5]octane-6-carboxylicacidbenzylester phenylmethyl1-oxa-6-azaspiro[2.5]octane-6-carboxylate benzyl1-oxa-6-azaspiro[2.5]octane-6-carboxylate 6-benzyloxycarbonyl-1-oxa-6-azaspiro[2.5]octane

    Molecular Formula: C14H17NO3

    Molecular Weight: 247.29

    MDL Number: MFCD11976640

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Spiro Compounds

    Product Description:
    Benzyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate is a heterocyclic spiro compound featuring a fused oxirane (epoxide) ring and an azetidine ring system. It serves as a versatile and valuable building block in medicinal chemistry and organic synthesis. The molecule contains a protected amine (as a carbamate) and a highly reactive epoxide moiety, making it a bifunctional intermediate. Its primary application is in the synthesis of complex pharmaceutical agents. The spirocyclic azetidine scaffold is of significant interest in drug discovery due to its potential to improve metabolic stability, solubility, and binding affinity of drug candidates. The reactive epoxide ring allows for further functionalization through ring-opening reactions with various nucleophiles, enabling the rapid construction of diverse molecular libraries. This compound is a key precursor for developing novel bioactive molecules, particularly those targeting central nervous system disorders and other therapeutic areas. It is typically handled as a research chemical under controlled laboratory conditions due to the reactivity of the epoxide group.
    Physical Properties
    mg g kg ml l t