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    76186-04-4

    Catalog No. EBD2204971

    CAS 76186-04-4

    Name (S)-4-isopropyl-1,3-thiazolidine-2-thione

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    Basic Information

    Synonyms: (S)-4-isopropyl-2-thio-1,3-thiazolidine (S)-4-Isopropylthiazolidine-2-thione

    Molecular Formula: C6H11NS2

    Molecular Weight: 161.29

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Sulfides and Thioethers

    Product Description:
    (S)-4-Isopropylthiazolidine-2-thione, with CAS number 76186-04-4, is a chiral heterocyclic compound featuring a thiazolidine-2-thione core structure with an isopropyl substituent at the 4-position. It is a solid compound that serves as a versatile chiral building block and auxiliary in organic synthesis. This compound is primarily utilized as a key chiral intermediate in the synthesis of various pharmaceuticals. Its sulfur-containing heterocyclic structure and defined stereochemistry make it valuable for constructing complex molecules, particularly in the development of drugs where chirality is crucial for biological activity. It is often employed in the preparation of β-lactam antibiotics and other bioactive molecules requiring specific stereocenters. As a chiral synthon, it is also relevant in the field of asymmetric synthesis, where it can act as a precursor or auxiliary to induce stereoselectivity in chemical transformations. Its applications extend to materials science research involving chiral ligands or functionalized heterocycles.
    Physical Properties

    Melting Point: 69-71 °C

    Boiling Point: 223.3 °C at 760 mmHg

    Flash Point: 88.9 °C

    Density: 1.17 g/cm3

    mg g kg ml l t