2-Amino-1-phenylethanol, CAS No. 7568-93-6

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7568-93-6

Catalog No. EBD916

CAS 7568-93-6

Name 2-Amino-1-phenylethanol

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Basic Information

Synonyms: 2-Amino-1-phenylethanol a-(Aminomethyl)benzenemethanol a-(Aminomethyl)benzylAlcohol Benzenemethanol,α-(aminomethyl)- b-Hydroxyphenethylamine dl-β-Phenyl-β-hydroxyethylamine β-hydroxy-Phenethylamine β-hydroxy-β-phenyl-Ethylamine phenylethanolamine dl-phenylglycinol 2-hydroxy-2-phenylethylamine (delta)-2-Amino-1-phenylethanol alpha-(Aminomethyl)benzylalcohol

Molecular Formula: C8H11NO

Molecular Weight: 137.18

MDL Number: MFCD00008137

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Amino-1-phenylethanol is an organic compound featuring both a primary amine and a secondary alcohol functional group attached to a phenyl-substituted ethane backbone. It exists as a chiral molecule, often used in its racemic form or as a precursor for chiral synthesis. This compound is primarily utilized as a versatile pharmaceutical intermediate. Its structure makes it a key building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those belonging to the class of adrenergic agents (e.g., certain decongestants and bronchodilators). The amino alcohol moiety is a common pharmacophore in drug molecules targeting the sympathetic nervous system. As a bifunctional chiral synthon, it is also employed in organic synthesis for constructing more complex molecules, serving as a precursor for ligands or other fine chemicals. Standard safety precautions for handling amines and alcohols should be observed during its use.

Physical Properties

Melting Point: 56-58 °C(lit.)

Boiling Point: 160 °C/17 mmHg(lit.)

Refractivity: 1.558-1.56

Analytical Data

Appearance: white solid