(S)-(-)-tryptophan methyl ester hydrochloride, CAS No. 7524-52-9

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7524-52-9

Catalog No. EBD4364

CAS 7524-52-9

Name (S)-(-)-tryptophan methyl ester hydrochloride

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Basic Information

Synonyms: L-tryptophanmethylesterhydrochloride H-Trp-OMe.HCl H-Trp-OMe*HCl (2S)-3-(1H-indol-3-yl)-1-methoxy-1-oxopropan-2-aminium H-Trp-OMe·HCl MethylL-tryptophanatehydrochloride H-Trp-OMe*hydrochloride (S)-(-)-tryptophanmethylesterhydrochloride

Molecular Formula: C12H15ClN2O2

Molecular Weight: 254.71

MDL Number: MFCD00066134

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

L-Tryptophan methyl ester hydrochloride is a derivative of the essential amino acid L-tryptophan, where the carboxylic acid group is esterified to a methyl ester and the compound is supplied as a hydrochloride salt. This modification enhances its lipophilicity and reactivity compared to the parent amino acid, making it a versatile building block. Its primary application is in pharmaceutical research and development as a key intermediate for the synthesis of more complex bioactive molecules. It serves as a crucial precursor for peptides and peptidomimetics that incorporate the tryptophan moiety, which is important for interactions with biological targets due to its large indole side chain. This compound is particularly valuable in medicinal chemistry for constructing drug candidates targeting the central nervous system, among other therapeutic areas. As a protected form of L-tryptophan, it is also used in the synthesis of natural products and in the preparation of specialized biochemical reagents. Handling requires standard precautions for laboratory chemicals, and it should be stored in a cool, dry place.

Physical Properties

Melting Point: 218-220 °C(lit.)

Refractivity: 19.5 ° (C=5, MeOH)

Storage: -15°C

Analytical Data

Appearance: White to off-white powder