(L)-leucine methyl ester hydrochloride, CAS No. 7517-19-3

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7517-19-3

Catalog No. EBD875188

CAS 7517-19-3

Name (L)-leucine methyl ester hydrochloride

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Basic Information

Synonyms: H-L-Leu-OMehydrochloride (L)-leucinemethylesterhydrochloride L-Leucinemethylesterhydrochloride L-LeucineMethylesterHCl MethylL-leucinatehydrochloride H-Leu-OMe.HCl H-Leu-OMe*HCl L-Leucinemethylestherhydrochloride (S)-2-AMINO-4-Methyl-PENTANOICACIDMethylESTERhydrochloride L-LeucinemethylesterhydrochlorideSalt Leucinemethylesterhydrochloride LEUCINE-OMEHCL H-LEU-OMEHCL Leuoome.hcl (2S)-1-methoxy-4-methyl-1-oxopentan-2-aminium methylleucinatehydrochloride

Molecular Formula: C7H16ClNO2

Molecular Weight: 181.66

MDL Number: MFCD00012494

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Leucine methyl ester hydrochloride is a derivative of the essential amino acid L-leucine, where the carboxylic acid group is esterified with methanol and the amino group is present as a hydrochloride salt. This modification enhances its lipophilicity and stability, making it a versatile building block. Its primary application is in the field of peptide synthesis and pharmaceutical research. As a protected amino acid derivative, it serves as a crucial intermediate for the solid-phase and solution-phase synthesis of peptides and peptidomimetics. It is also used in the preparation of various bioactive compounds and prodrugs. Furthermore, it finds use in biochemical studies and as a reference standard. The compound is a white to off-white crystalline powder. It is hygroscopic and should be stored under inert conditions. Standard safety precautions for handling amino acid derivatives and hydrochloride salts should be observed.

Physical Properties

Melting Point: 151-153 °C(lit.)

Boiling Point: 169.2 °C at 760 mmHg

Flash Point: 42.7 °C

Density: 0.955 g/cm3

Solubility: H2O: 50 mg/mL, clear, colorless

Refractivity: 13 ° (C=2, H2O)

Storage: 0-6°C

Analytical Data

Appearance: Crystalline