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    75073-15-3

    Catalog No. EBD1078850

    CAS 75073-15-3

    Name 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid ethyl ester

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    Basic Information

    Synonyms: 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylicacidethylester ethyl7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate ethyl7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 7-chloro-3-ethoxycarbonyl-6-fluoro-4-oxo-1,4-dihydro-quinoline ethyl7-chloro-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylate ethyl7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 6-fluoro-7-chloro-4-quinolone-3-carboxylicacidethylester

    Molecular Formula: C12H9ClFNO3

    Molecular Weight: 269.66

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    7-Chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester is a key fluorinated quinolone carboxylic acid derivative. It serves as a crucial advanced intermediate in the synthesis of third-generation fluoroquinolone antibiotics, most notably **Norfloxacin**. The compound features the core 4-oxo-1,4-dihydroquinoline-3-carboxylic acid scaffold, which is essential for the antibacterial activity of this drug class, with the chlorine and fluorine substituents at the 7- and 6- positions, respectively, being critical structural motifs. Its primary and well-defined industrial application is in the pharmaceutical manufacturing sector. It is a high-value building block specifically designed for constructing the final active pharmaceutical ingredient (API) through subsequent synthetic steps, such as piperazination at the 7-position. This places it squarely in the category of a pharmaceutical intermediate rather than a general-purpose chemical. While its predominant use is as a pharmaceutical intermediate, its defined structure as a functionalized heterocycle (quinolone) also qualifies it as a specialized organic synthesis building block for medicinal chemistry research focused on quinolone analogs.
    Physical Properties
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